Belgium's second largest city is also its most hip. Always creative - in the 16th and 17th century, it was the great masters such as Rubens and Anthony Van Dyck; in the 20th and 21st centuries, its fashion designers like the world-famous Antwerp Six. There is much to do of a cultural nature, but the city is also well worth a visit for its excellent restaurants, bars and clubs, as well as for its shopping.